A recent study published in Frontiers Endocrinology revealed that Body Shape Index (ABSI) is associated with the risk of Diabetes Kidney Disease (DKD) in patients with Type 2 Diabetes Mellitus (T2DM). The study aimed to determine the relationship between ABSI and DKD in patients with T2DM.

Data from 2,598 patients having T2DM enrolled in National Metabolic Management Centers of Yuhuan Second People’s Hospital and Taizhou Central Hospital were collected, and a cross-sectional study was conducted during 2017 and 2024. To evaluate the association between ABSI and DKD, multivariate logistic regression models were used. To explore dose-response patterns, restricted cubic splines (RCS) were used.

It was found that  1,030 participants were diagnosed with DKD. Across ABSI tertiles, the prevalence of DKD was found to be increased 44.7% in the highest tertile (T3), 38.5% in the middle tertile (T2), and 35.8% in the lowest tertile (T1). The association of higher ABSI with a greater risk of DKD (OR = 1.24; 95% CI: 1.05–1.50; P = 0.022) was observed after confounder adjustments. Higher risk of DKD was found to be highest in ABSI tertile compared to that of the lowest tertile (OR = 1.24; 95% CI: 1.01–1.52; P = 0.041). A positive linear relationship between ABSI and DKD risk was found by RCS analysis.