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Is there any efficacy of the automated insulin delivery systems in effectively and safely improving the blood sugar in children with type 1 diabetes? The answer is affirmative based on a study published in The Lancet: Diabetes and Endocrinology.

The study enrolled 98 children aged 2–6 years who required at least six units of insulin daily.

Results revealed that time spent in the target blood glucose range (70–180 mg/dL) increased significantly during auto mode (68.3%) compared to manual mode (58.3%). Average HbA1c improved to 7.0% in auto mode versus 7.6% in manual mode.

Although nine serious adverse events were reported, none were linked to the study device. No cases of severe hypoglycemia occurred.

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Key highlights

Automated insulin delivery not only provides superior glucose control but also offers a safe option for young children.

Source

Battelino T, Kuusela S, Shetty A, et al. Efficacy and safety of automated insulin delivery in children aged 2-6 years (LENNY): an open-label, multicentre, randomised, crossover trial. Lancet Diabetes Endocrinol. 2025;13(8):662-673. doi: https://doi.org/10.1016/S2213-8587(25)00091-9 

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Safety and Efficacy of Automated Insulin Delivery
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An open-label, multicentre, randomized crossover trial reported the safety and efficacy of automated insulin delivery systems in effectively and safely improving blood glucose levels in very young children with type 1 diabetes. 

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