Bipolar catheter ablation provides an effective approach for ventricular arrhythmias originating from intramural sites. Published in the Journal of Cardiovascular Electrophysiology, the study highlights strong efficacy and safety in both first-time and repeat ablation procedures.

The analysis included 19 patients (median age 66 ± 11 years; 11% female; median ejection fraction 42% ± 16%) who underwent 21 bipolar ablation procedures. Sixteen procedures targeted ventricular tachycardia (VT) or VT storm, and five addressed symptomatic premature ventricular contractions (PVCs). Nearly half of the procedures (48%) were performed as the patient’s first ablation attempt.

The interventricular septum was the primary site of ablation (11/21), followed by combined epi-endocardial sites (9/21) and the papillary muscle (1/21). Acute procedural success was achieved in 17 cases. One patient developed AV block and four patients with initially successful ablation experienced recurrence and during a median follow-up of 12 ± 6 months. Overall, bipolar catheter ablation demonstrated high effectiveness and a favorable safety profile, making it a valuable option for managing challenging intramural arrhythmias.