A study in the European Journal of Medical Research suggested that the Body Roundness Index (BRI) plays a role in predicting cognitive impairment (CI) in middle-aged and elderly individuals with type 2 diabetes (T2D).
The study investigated the relationship between BRI and CI in middle-aged and elderly patients with T2D.
Researchers conducted a general statistical description of the study population. The association between BRI and CL was explored using logistic analysis. To further investigate this association, researchers employed Sensitivity analyses and restricted cubic spline (RCS) methods.
Results showed that the prevalence of CI was 44.8% (590 out of 1318 participants). The study reported a positive association between BRI and CI. Women with elevated BRI had a higher CI risk in both the crude (OR: 1.46) and fully adjusted models (OR: 1.26); however, men did not have a higher risk in the fully adjusted model (OR: 1.04).
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Key highlights
- The Body Roundness Index (BRI) is a reliable tool for predicting cognitive impairment (CI) in individuals with type 2 diabetes (T2D).
- Women had a significantly stronger association between BRI and CI than men.
- BRI can be a practical screening tool in clinical settings to help identify middle-aged and elderly patients with T2D who are at risk of cognitive decline.
Source
Liu, Y., Qiu, H., Zhang, M. et al. Sex-specific association between body roundness index and cognitive impairment among hospitalized middle-aged and elderly patients with type 2 diabetes in China: a cross-sectional analysis. Eur J Med Res 30, 570 (2025). https://doi.org/10.1186/s40001-025-02849-0
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Body Roundness Index plays a role in predicting cognitive impairment in middle-aged and elderly individuals with type 2 diabetes.
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