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Real-time continuous glucose monitoring (CGM) can accelerate glycemic improvement in adults with type 2 diabetes using basal insulin. Findings from the MOBILE study, published in BMJ Open Diabetes Research & Care, showed that replacing blood glucose monitoring (BGM) with CGM led to faster and greater reductions in HbA1c and improved daily glucose stability.

In this 3-month randomized analysis, 175 adults were assigned to either CGM (n=116) or BGM (n=59). Average HbA1c dropped from 9.1% to 8.0% with CGM, compared with 9.0% to 8.5% with BGM, reflecting an adjusted difference of −0.6% (p < 0.001). CGM increased time in range by 9.3% and reduced time above 250 mg/dL by 5.8%, with no rise in time below 70 mg/dL or hypoglycemia events.

Notably, significant CGM improvements emerged within the first week of use, underscoring its potential for more immediate and effective diabetes management in patients treated with basal insulin.
 

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Key highlights
  • Analysis from the MOBILE study included 175 adults with type 2 diabetes on basal insulin.
  • Continuous glucose monitoring (CGM) use lowered HbA1c by 0.6% more than blood glucose monitoring (BGM) over 3 months (p < 0.001).
  • Time in range (70–180 mg/dL) improved by 9.3%, and time above 250 mg/dL decreased without increasing hypoglycemia risk.
  • CGM metrics improved within the first week of use.
Source

Martens TW, Beck RW, Griffen C, et al. Rapid improvements in glycemic management with use of continuous glucose monitoring in adults with type 2 diabetes treated with basal insulin: 3-month analysis of the MOBILE study. BMJ Open Diabetes Res Care. 2025;13:e005469. doi:10.1136/bmjdrc-2025-005469

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Continuous Glucose Monitoring Outperforms Fingerstick Testing for Rapid Glycemic Control
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Switching from fingerstick testing to continuous glucose monitoring yields faster HbA1c reduction and greater time in range in adults on basal insulin

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