Diabetes-related foot ulcers (DFUs) are frequently accompanied by significant emotional burden and challenges in self-management. A systematic scoping review published in Diabetic Medicine evaluated the emotional consequences of DFUs and the psychosocial factors influencing disease progression, management, and self-care behaviors.

The review followed Arksey and O’Malley’s six-stage framework and Joanna Briggs Institute guidance, and was reported according to PRISMA-ScR standards. Forty-nine studies met inclusion criteria, comprising 28 cross-sectional studies, 13 qualitative studies, 5 prospective studies, 2 randomized controlled trials, and 1 case study.

Across study designs, individuals living with DFUs experienced heightened emotional distress and substantially reduced health-related quality of life, largely attributed to physical limitations, difficulties in diabetes self-management, and concerns about future complications. Psychosocial influences included low self-efficacy, feelings of powerlessness, loss of independence, and perceived burdensomeness. Disparities related to gender, socioeconomic status, and cultural background further influenced emotional outcomes and self-care behaviors.

The findings indicate that psychosocial factors substantially influence emotional well-being, treatment adherence, and wound healing in adults with DFUs. The review suggests that integrating psychosocial assessment, tailored education, and emotional support into routine care may support self-care and quality of life.