Poor glycemic control was strongly associated with adverse lipid patterns in adults with type 2 diabetes mellitus (T2DM). Published in the International Journal of Life Sciences Biotechnology and Pharma Research, this cross-sectional study examined how glycated hemoglobin (HbA1c) relates to lipid disturbances that contribute to cardiovascular risk.

The study assessed 114 adults with T2DM attending a tertiary care hospital. Dyslipidemia was highly prevalent: 61.4% had elevated triglycerides, 64.9% had reduced HDL-C, and 58.8% showed increased LDL-C. Higher HbA1c values correlated significantly with total cholesterol, triglycerides, LDL-C, and VLDL-C, while showing a negative correlation with HDL-C (r = –0.298, p = 0.002).

Patients with poor glycemic control (HbA1c ≥ 9%) had markedly worse lipid abnormalities compared with those achieving HbA1c < 7%, indicating a clear relationship between chronic hyperglycemia and atherogenic dyslipidemia.

These findings reinforce the need for integrated management of glucose and lipid parameters in T2DM to reduce cardiovascular complications and improve long-term metabolic outcomes.