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CGM during late pregnancy may help predict complications in women with type 1 diabetes. A retrospective analysis of 87 singleton pregnancies, published in the Journal of Diabetes Science and Technology, revealed that glucose trends from 24 to 39 weeks’ gestation were linked to adverse outcomes in 71% of participants.

Women who developed HDP showed a significantly higher mean glucose concentration and time above range, along with reduced time in range between 24 and 37 weeks (P < .05). The divergence in CGM metrics was most pronounced between 28 and 30 weeks, when insulin resistance typically peaks.

Those delivering large-for-gestational-age (LGA) infants had lower time below the range between 24 and 35 weeks, suggesting different glycemic dynamics influence fetal growth. CGM data from the late second to early third trimester may help identify pregnancies at higher risk for HDP or LGA. Detecting these trends early can support more timely and personalized management. 
 

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Key highlights
  • Continuous glucose monitoring (CGM) data from 87 pregnant women with type 1 diabetes were analyzed between 24 and 39 weeks of gestation.
  • Higher time above range and lower time in range were linked to hypertensive disorders of pregnancy (HDP).
  • CGM metrics diverged most strongly at 28 to 30 weeks, suggesting a potential window for intervention.
Source

Fisher SA, Pavan J, Villa-Tamayo MF, et al. Continuous Glucose Monitoring and Maternal and Neonatal Morbidity in Pregnant People With Type 1 Diabetes. J Diabetes Sci Technol. Published online November 4, 2025. doi:10.1177/19322968251388119

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Late-Pregnancy CGM Patterns Reveal Early Warning Signs of Complications in Type 1 Diabetes
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Continuous glucose monitoring in the late second and early third trimester helps detect risk of hypertensive disorders and fetal overgrowth

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