A recent study published in Diabetes Research and Clinical Practice revealed that poorer glycemic control, increased Diabetes complications, and utilization of anti-glycemic medications are higher in type 2 diabetes patients, highlighting the need for medication that controls glycemia as well as reduces weight. The study aimed to look into how weight status is associated with diabetes related complications, glycemic control, and anti-hyperglycemic medication use in T2DM adults.

Researchers conducted a cross-sectional study including 13,589 T2DM adult patients using Australian National Diabetes Audits (ANDA), and the data were analyzed between 2015 and 2022. The association of glycemic control and diabetes complications with weight status was explored with the data collected.

Results showed that 71% of patients had HbA1c > 7 %. Patients with obesity showed a greater odds of being moderately above target (HbA1c 7.1–9 %) or greatly above target (HbA1c > 9 %) glycemia. Despite the use of a greater number of anti-hyperglycemic drugs, a greater likelihood of having peripheral disease, diabetic foot ulcers, and cardiovascular disease was seen in patients with obesity.