Pregnancy appears to influence long-term outcomes in women with type 1 diabetes. These results from the Finnish Diabetic Nephropathy Study were presented at the European Association for the Study of Diabetes (EASD) 2025.
The analysis included 2,487 women with type 1 diabetes, grouped by parity: none (41.1%), one (23.8%), two (24.4%), and three or more pregnancies (10.7%). Data on diabetic complications and mortality were retrieved from national registries through 2020, with a mean follow-up age of 53.8 years. Subgroup analyses in women aged ≥45 years confirmed the robustness of the findings.
Multiparous women demonstrated significantly lower odds of cardiovascular events, kidney replacement therapy, and death compared with nulliparous women. Those with one pregnancy showed reduced risks of heart failure and mortality but not other complications.
The findings suggest that pregnancy may encourage tighter glucose management, contributing to long-term benefits. These results provide clinically useful context for family planning discussions with women living with type 1 diabetes.