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Significant underexpansion was consistently observed after deployment of balloon-expandable transcatheter valves in this prospective analysis. Published in JACC: Cardiovascular Interventions, the report evaluated whether routine post-dilatation could optimize frame geometry and support early hemodynamic outcomes.

The investigation included 200 adults undergoing transcatheter aortic valve implantation for native aortic stenosis. All individuals underwent routine post-dilatation, and frame measurements were obtained before and after the procedure using fluoroscopy. Marked underexpansion was seen at the mid-frame level, and post-dilatation produced substantial improvement in expansion and expected foreshortening.

Short-term outcomes were favorable. At 30 days, all-cause mortality was 1.5%, stroke occurred in 3.0%, the mean gradient remained low at 10.7 ± 4.2 mmHg, and no patient demonstrated more than mild paravalvular leak.

These findings suggest that routine post-dilatation can improve early structural and functional performance of balloon-based TAVR systems. Longer-term studies will be necessary to determine its impact on durability and late hemodynamics.

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Key highlights
  • All implanted valves showed measurable underexpansion before post-dilatation.
  • Post-dilatation increased frame expansion and reduced foreshortening across valve sizes.
  • Thirty-day outcomes included low mortality at 1.5% and stroke at 3.0% with no more than mild paravalvular leak.
Source

Krishnamoorthy P, Onishi T, Singh S, et al. Double inflation (“double tap”) on valve expansion and short-term outcomes after the latest-generation balloon-expandable TAVR. JACC Cardiovasc Interv. Published online November 16, 2025. doi:10.1016/j.jcin.2025.11.004

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Post-dilatation Improves Frame Expansion and Geometry in Balloon TAVR
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Routine post-dilatation corrected underexpansion and enhanced early valve performance in a contemporary balloon-expandable system

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