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A recent study published in the Journal of Gastrointestinal Surgery demonstrated that preoperative hospitalization alone for glucose control may not offer significant benefits for diabetes patients undergoing colorectal or gastric cancer surgery.  

The study aimed to determine how effective preoperative hospitalization is in controlling glycemia in T2D patients undergoing surgery for colorectal or gastric cancer.

Data of patients (n=376) who underwent gastric or colorectal cancer surgery were collected, and a multi-institutional retrospective cohort study was conducted. Outcomes of patients who were hospitalized for glycemic control pre-surgery were compared with those of non-hospitalized patients. Postoperative infectious complications of Clavien–Dindo grade (CD) more than 1 were the primary outcome. In contrast, postoperative overall complications of CD more than 2, perioperative mean insulin usage per day, and perioperative mean blood glucose level per day were secondary outcomes. 
Reduction in glycemic control did not lower postoperative infectious complications and the overall postoperative complications (OR 1.05, 95% CI 0.55–2.00, P=0.875). Between hospitalized and non-hospitalized groups, blood glucose was not different (POD-1: P=0.088, POD0: P=0.602, POD1: P=0.169, POD2: P=0.500, POD3: P=0.478). Higher postoperative insulin usage per day was seen in the hospitalized group compared to the non-hospitalized group. 

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Key highlights
  • No significant reduction in postoperative infectious complications was observed with preoperative hospitalization for glycemic control (OR = 1.05, P = 0.875).
  • Perioperative blood glucose levels were not significantly different between hospitalized and non-hospitalized groups.
  • Higher postoperative insulin usage was required in the hospitalized group, despite no improvement in surgical outcomes.
Source

Jikihara S, Hoshino N, Hida K, et al. Effectiveness of preoperative hospitalization for glycemic control in patients with diabetes undergoing gastric or colorectal cancer surgery. J Gastrointest Surg. 2025;29(9):102144. https://doi.org/10.1016/j.gassur.2025.102144 

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Preoperative hospitalization alone for glucose control may not offer significant benefits for diabetes patients undergoing colorectal or gastric cancer surgery.

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