Transradial catheterization is widely used for coronary angiography, and the radial artery (RA) is frequently selected as a conduit for coronary artery bypass grafting (CABG). Whether a previously catheterized RA (CRA) remains an optimal conduit for CABG has been uncertain. A systematic review and meta-analysis published in the Heart, Lung, and Circulation evaluated graft patency associated with prior transradial catheterization.

A systematic search of MEDLINE, Embase, and Scopus identified comparative studies evaluating CRA versus non-catheterized radial artery (NCRA) grafts. The primary outcome was RA graft patency. Random-effects models generated pooled effect estimates, with heterogeneity assessed using I². Small-study effects were evaluated using funnel plot and Egger’s test, and influence analyses were conducted.

Among 1,661 screened studies, four observational studies involving 400 patients (175 CRA and 379 NCRA grafts) were included. Mean time from catheterization to CABG was 27.4±16.0 days, and follow-up imaging occurred at 2.06±1.88 years. CRA grafts demonstrated lower patency (73.2% vs 83.9%) and higher graft failure risk (OR 1.82; 95%CI 1.26-2.61; p=0.001; I²=33%).

Prior transradial catheterization was associated with reduced RA graft patency. Prospective controlled studies are needed to clarify patient and procedural factors influencing risk.