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Multimorbidity is defined as having two or more chronic conditions. In the US Veterans Health Administration (VHA), new research reveals stark disparities in the development of type 2 diabetes mellitus (T2DM) linked to comorbidity burden and race.

The data for this study, published in Diabetology, was collected from over 10.4 million Veterans. The patients were followed for decades to assess how comorbidities influenced diabetes prevalence and incidence. From the cohort, nearly one in four veterans had T2DM. Veterans with one comorbidity were 1.8 times more likely to have diabetes, while those with two or more had 2.5 times greater odds, even after adjusting for demographics and clinical factors.

Notably, racial disparities were prominent predisposing factors. Compared to White Veterans, Black and Hispanic Veterans each had 1.6 times higher odds of diabetes. When multimorbidity was combined with advancing age, the risks were elevated even further. Veterans aged 50–64 had nearly fourfold higher odds of developing diabetes.

Analysis of costly multimorbid conditions, such as hypertension, depression, and chronic pulmonary disease, revealed higher frequencies among diabetic patients across all racial groups. Yet, Black Veterans had disproportionate burdens of renal failure, complicated hypertension, and psychiatric conditions, while Hispanics showed higher rates of depression alongside diabetes.

These findings conclude that multimorbidity doubles the odds of diabetes and that racial and ethnic disparities persist even in an equal-access system like the VHA. Targeted, people-centered strategies, including improved chronic disease management and tailored interventions for minority Veterans, are needed.

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Key highlights
  • Veterans with more than 2 comorbidities had 2.5 times higher odds of developing diabetes compared with those without comorbidities.
  • Hispanic and Black Veterans showed significantly higher risks of diabetes than White Veterans, despite equal access to care.
  • The findings highlight the need for targeted interventions to address disparities in multimorbid diabetes progression within the VHA.
Source

Frey LJ, Gebregziabher M, Bishu KG, Youngblood B, Obeid JS, Shi J, Alba PR, DuVall SL, Blasy CD, Halbert CH. Multimorbidity Burden in Veterans with and Without Type 2 Diabetes Mellitus: A Comparative Retrospective Cohort Study. Diabetology. 2025; 6(9):88. https://doi.org/10.3390/diabetology6090088 

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Racial risk factors in type 2 diabetes
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A national VHA study shows that multimorbidity more than doubles the odds of type 2 diabetes, with Hispanic and Black Veterans facing greater risk.

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