A recent study published in Diabetes Research and Clinical Practice highlighted the impact of sex differences in vascular, nonvascular, and mortality for type 2 diabetes (T2DM) patients, suggesting the need for sex specific therapies for managing T2DM.

The study aimed to determine the risk of macrovascular, microvascular, and nonvascular complications in T2DM.

A total of 4923 Patients were included in the study. Hazard ratios for microvascular, macrovascular, mortality, and nonvascular complications in women were compared with men using Cox regression models.

In women, the risk of all-cause death was found to be lower compared to men. The risk of major macrovascular events and cancer was 59% lower in women. A higher risk of fracture was seen in women compared to men. In the risk of microvascular events, no difference was observed based on sex. For cancer and fractures, the risk increases with age.