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Lower “felt” temperatures, measured through apparent temperature and windchill, appear to act as short-term environmental triggers for acute type A aortic dissection (ATAAD). Published in the European Journal of Cardio-Thoracic Surgery, this multicentre German study examined whether real-world thermal stress contributes to dissection onset.

The analysis included confirmed ATAAD cases from 1996 to 2016, with meteorological data retrieved for the two weeks preceding symptom onset. Short-term associations were evaluated using distributed lag non-linear models within a case-crossover design. Lower apparent temperature and elevated windchill were consistently linked to higher ATAAD odds, with the strongest effects observed three to four days before clinical presentation. Additional contributors included higher atmospheric pressure and low dew point, while lower humidity and minimal cloud cover were associated with reduced odds.

The findings highlight the importance of “felt” thermal stress in cardiovascular risk assessment and suggest that sudden cold conditions may warrant heightened vigilance in susceptible individuals.

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Key highlights
  • Lower apparent temperature and higher windchill showed the strongest association with acute type A aortic dissection.
  • Risk peaked three to four days before symptom onset and declined afterward, with no increase at milder temperatures.
  • Higher atmospheric pressure and low dew point raised odds, while lower humidity and low cloud cover showed modest protective effects.
Source

Kletzer J, Van Kampen A, Peterss S, et al. Weathering the aorta: The impact of environmental factors on acute aortic dissection. Eur J Cardiothorac Surg. Published online November 12, 2025. doi:10.1093/ejcts/ezaf403

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Sudden Cold Exposure May Trigger Acute Aortic Dissection Events
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Apparent temperature and windchill strongly linked to short-term increases in acute type A aortic dissection
 

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