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Telemedicine strategies improved anticoagulation management without increasing safety risks in older adults. The findings were presented at the European Society of Cardiology Congress 2025.

Patients on oral anticoagulants require close monitoring to maintain therapeutic levels and prevent thromboembolic events. A systematic review analyzed 39 clinical trials including 119,734 patients, with an average age of 75 years, evaluating telemedicine interventions such as self-testing with remote mobile management, computer-assisted dosing, laboratory-guided dose adjustments, and multitasking applications.

Use of telemedicine was associated with a significant increase in time in therapeutic range for patients on warfarin (mean difference 4.61, 95% confidence interval [1.60–7.62]). A trend toward reduced thromboembolic events was observed (relative risk 0.85, 95% CI [0.72–1.00]), while no differences were seen in mortality (RR 0.98, 95% CI [0.88–1.10]) or major bleeding (RR 0.92, 95% CI [0.81–1.05]).

These results indicate that telemedicine is a safe and effective approach to managing patients on oral anticoagulation, supporting wider adoption of remote monitoring and digital tools to improve therapeutic outcomes in clinical practice.
 

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Key highlights
  • Telemedicine interventions increased time in therapeutic range for patients on warfarin.
  • Trend toward lower thromboembolic events observed, though mortality remained unchanged.
  • No increase in major bleeding risk with remote anticoagulation management.
  • Remote monitoring and mobile applications may optimize anticoagulation care in older adults.
Source

Costa AAA, Pires LM, Kopittke L, et al. Telemedicine for oral anticoagulation management: a systematic review and meta-analysis of effectiveness and safety. Presented at: ESC Congress 2025; August 29-September 1, 2025; London, United Kingdom. https://esc365.escardio.org/presentation/305379 

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Telemedicine Improves Anticoagulation Management in Older Adults
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Systematic review of 39 trials shows remote strategies enhance time in therapeutic range without raising major bleeding risk

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