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Key highlights
- Analysis of 15,519 adults examined associations between cardiovascular phenotypes, brain structure, and cognition.
- Ventricular geometry showed the strongest relationship with hippocampal volume and cognitive performance.
- Findings suggest cardiac structural features may influence brain health, highlighting heart–brain interconnection.
Source
Masci PG, Freydin M, Andreozzi G, et al. Left ventricular geometry, brain architecture, and cognition: an observational study. Eur Heart J. Published online October 9, 2025. doi:10.1093/eurheartj/ehaf722
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UK Biobank analysis links cardiac ventricular geometry with hippocampal volume and cognitive performance in older adults
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